Abstract

In patients with acute epidermal necrolysis, the most frequent diagnosis is Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and less frequently Toxic Epidermal Necrolysis-like Lupus Erythematosus (TEN-LE). Both groups of conditions present with erythema, papules and/or bullae, and sheet-like detachment of skin.1 Proposed features to support TEN-LE include the absence of 'high-risk' drug use, UV-exposure, an insidious onset of symptoms, a photo-distributed cutaneous eruption, minimal mucosal involvement, and autoimmune serology consistent with systemic lupus erythematosus (SLE).

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