Toxic epidermal necrolysis in patients with malignancies

Abstract

Curigliano and colleagues recently published an interesting letter focusing on the appearance of toxic epidermal necrolysis (TEN) in a breast cancer patient [1]. TEN manifestations started 5 days following the administration of voriconazole given for an invasive pulmonary aspergillosis which followed chemotherapy administration, suggesting the possibility for a role of voriconazole in TEN pathogenesis. This patient was successfully treated with human intravenous immunoglobulin in an intensive care unit.