Abstract
The healthy life of human depends on healthy foods as well as food safety. But unethical practice of textile dyes as adulterant damages the safety of food chain. Textile industries also uses textile dyes to full-fill increase demand of textile products, which produce large waste dye as effluent in ground water due to inefficiency of dying process and causes serious environmental pollution. In this study, we investigated the toxic effects of two textile reactive dyes Levafix Blue CA and Levafix Amber CA by in vivo experiments in mice. Mice were administered Levafix Blue CA and Levafix Amber CA textile dyes at a single oral dose of 0.04 g/kg daily for 21 days to observe any toxic effect of those dyes in mice. The toxic effects were evaluated by measuring the serum activity of aspartate amino-transferase (AST), glutamate pyruvate transaminase (ALT), serum total bilirubin (STBI), serum creatinine (SCR), serum urea (SBUN) and also histopathology of liver and kidney. The levels of AST, ALT, STBI, SBUN and SCR were found to be increased by both Levafix Blue CA and Levafix Amber CA. Histopathological examination of liver and kidney revealed inflammation in mice.
Highlights
This paper describes the effects of the two textile dyes on the activity of some organs of mice
Aspartate aminotransferase (AST) [AST formerly was called serum glutamic oxaloacetic transaminase (SGOT)], alanine aminotransferase (ALT) [ALT used to be called serum glutamic-pyruvic transaminase, or SGPT], serum urea and serum creatinine were determined by biochemical auto analyzer (Dimension Xpand Plus, Siemens, Germany)
After treating with Levafix Blue CA reactive dye a mild inflammation of liver was observed in two mice (No 1 and 3) but there was no significant effect on third one (No 2) (Figure 3 and 4, respectively)
Summary
It began a couple of decades ago and this practice is increasing day by day. The problem of adulteration persists at every level of foods from preparation to consumption. Textile dyes use as coloring agents instead of food grades colorant due to cheapness of textile dyes. Consumption of adulterated food items severely affects the human health by producing many acute and chronic diseases. [2] A report by the ‘Poribesh Bachao Andolan’ disclosed that about 7.9 million (79 lakh) people in South Asia die every year by non-contagious diseases, and food adulteration is marked as one of the most important reasons. The report warned if this food adulteration cannot be prevented it will affect the mental growth in generation. The report warned if this food adulteration cannot be prevented it will affect the mental growth in generation. [1, 3]
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