Abstract
ABSTRACTThe use of VX and sarin as weapons of assassination and warfare raises important considerations for healthcare professionals who may encounter victims, bystanders, and responders who require prompt assessment and treatment. Chemical warfare agents such as VX and sarin constitute a considerable threat to the health of the civilian population, military personnel, and peacekeeping forces. Healthcare providers should recognize symptoms of nerve agent exposure, understand regional and international notification procedures for potential attacks, as well as the indications for and available supply of antidotal therapy.
Highlights
In February 2017, Kim Jong-Nam, the half-brother of North Korea’s ruler Kim Jong-Un, was allegedly assassinated inside the Kuala Lumpur airport
VX and sarin are odorless organophosphates developed as chemical warfare nerve agents
Persistent binding of VX and sarin to the active site irreversibly inhibits acetylcholinesterase, a process known as “aging.” Symptoms appear within a few seconds after exposure to vapor forms of VX or sarin, and within a few minutes to hours after exposure to liquid VX
Summary
ISSN: (Print) 2473-4306 (Online) Journal homepage: https://www.tandfonline.com/loi/ttxc. View related articles View Crossmark data Citing articles: 2 View citing articles.
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