Toxic anterior segment syndrome – A sequel of uneventful cataract surgery

Abstract

Toxic Anterior Segment Syndrome (TASS), previously known as sterile endophthalmitis and postoperative uveitis of unknown cause, was aptly termed as ‘toxic anterior segment inflammation’ by Monson et al.1 It is defined as a sterile, acute postoperative inflammatory reaction caused by a non-infectious substance that accidentally enters the anterior segment, resulting in toxic cellular and extracellular damage to the intraocular tissues that may occur following any kind of anterior segment surgery. It mostly occurs in outbreaks after uneventful cataract surgery, as it is the most commonly performed anterior segment surgery. The process typically starts 12–48 h after cataract/anterior segment surgery, and is limited to the anterior segment of the eye. A report of a case of secondary glaucoma with pseudophakic bullous keratopathy which occurred as a sequel of TASS after uneventful cataract surgery and thereby underwent filtering surgery along with penetrating keratoplasty is being presented.