Abstract

The persistence of a viral reservoir in HIV-1 infected patients under suppressive antiviral treatment has thus far prevented achieving a functional HIV-1 cure. Crucial in these initial strides to identify cure strategies is patient selection. Interventional research on cure in HIV-1 patients usually aims to demonstrate at least one of the following outcomes: a significant depletion of the inducible viral reservoir or the stable absence of renewed viral replication as the infected patient discontinues antiviral therapy.

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