Abstract

With increasing urbanisation, the dengue disease burden is on the rise in India, especially in large cities such as Mumbai. Current dengue surveillance in Mumbai includes municipal corporation carrying out specific activities to reduce mosquito breeding sites and the use of insecticides to suppress the adult mosquito populations. Clinical cases remain either underreported or misreported due to the restriction to government clinics, missing the large private health care sector. There is a need for an integrated approach to manage dengue outbreaks in Mumbai. There are various novel strategies available for use that can be utilised to improve disease detection, mosquito surveillance, and control of mosquito-borne diseases. These novel technologies are discussed in this manuscript. Given the complex ecosystem of mosquito-borne diseases in Mumbai, integrating data obtained from these technologies would support the ongoing mosquito control measures in Mumbai.

Highlights

  • Academic Editors: Luciana Barros de Arruda, Fabrício S

  • This platform has been used in Mexico for dengue surveillance and it made a significant impact on mosquito and disease control activities [101]

  • With growing human and mosquito populations and increasing incidence of dengue in large cities such as Mumbai, there is a need for an integrated response to reduce the impact of dengue on the local vulnerable population

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Summary

Introduction

Academic Editors: Luciana Barros de Arruda, Fabrício S. The frequency and magnitude of epidemic dengue have increased dramatically in the past 50 years as the viruses and their mosquito vectors have both expanded geographically in the tropical and sub-tropical regions of the world [6]. When the person is exposed to a different serotype, the existing antibodies do not provide a neutralising effect These heterotypic antibodies enhance the uptake of the virus by macrophages via the Fcγ receptor, enhancing the infection and in turn causing severe disease [14,20,21]. Other than traditional vector control methods, Viruses 2021, 13, 2436 there are various next-generation approaches under consideration or in use to reduce the impact of dengue and other mosquito-borne diseases. Long-term impacts of these approaches are being established, these novel strategies may provide a way forward for tackling these diseases

Dengue Burden in India
Dengue Surveillance in India
Dengue in Mumbai
Improvement
Supporting Dengue Diagnostics
Improved Entomological Surveillance
Use of Novel Mosquito Traps for Surveillance
Molecular Epidemiology to Support Surveillance
Improved Community Engagement and Response
Use of Novel Technologies for Mosquito Control and Transmission Prevention
Findings
Conclusions
Full Text
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