Abstract
This article presents the results of a study aimed at a developing an approach to the design of information infrastructure of medical institutions that use knowledge-based clinical decision support systems (CDSS). As a source of knowledge, we mainly consider the data stored in medical information system (MIS). The authors attempted to formulate an approach that will be flexible enough to allow engineers to realize almost any scenario of decision-support. To illustrate its practical use, we describe its application to one of the problems now being actively solved in the course of cooperation between ITMO University and Federal Almazov North-West Medical Research Centre, namely - development of a CDSS for the diagnostics of pulmonary arterial hypertension.
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