Abstract

Data for the efficacy of adjuvant chemotherapy in urothelial cancer comes from prematurely closed trials with poor accrual that have not yielded definitive conclusions about benefit. Yet, the potential activity reported in these trials has been promising enough to encourage investigators to pursue assessment of this treatment. In The Lancet Oncology, Cora Sternberg and colleagues1 report the results of the EORTC 30994 trial, which compared immediate versus deferred cisplatin-based combination chemotherapy after radical cystectomy in patients with urothelial carcinoma of the bladder.

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