Abstract

Two chiral diamines (3S)-3-anilinomethyl-1,2,3,4-tetrahydroisoquinoline (1) and (2R)-2-anilinomethylpiperidine (2) have been employed as chiral catalytic sources in the borane-mediated asymmetric reduction of prochiral ketones thus providing the resulting secondary alcohols in good enantiomeric purities (up to 81% ee).

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