Abstract
In a program aimed at establishing a common sequence of C-C bond-forming reactions for asymmetric construction of tetracyclic triterpenoid natural products and related synthetic systems, effort has been directed toward introducing C17β-substitution by late-stage functionalization of stereodefined "steroidal" D-ring vinylepoxides (spanning C14-C17). It has been found that cyanocuprates participate in syn-SN2' reactions that result in products bearing various C17β-substituents and containing a β-OH at C14.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
