Abstract
Separating racemates is still a great challenge for their similarity in chemical structures and physicochemical properties. Despite exhibiting a significant potential in the adsorption separation due to their intrinsic characteristics, hierarchically porous materials utilized in enantioseparation have rarely been reported to date. Furthermore, the molding of such materials together with their hybrid organic-inorganic monoliths is generally required to meet various prerequisites in diverse large-scale industrial applications, but without sacrificing their inherently hierarchical architectures. In this work, a three-dimensional hierarchically porous organic-inorganic composite was simply and feasibly prepared via integrating the micro/meso-porous hyper-cross-linked resin organic polymer (HROP) with macroporous silica gel sheet (SGS), followed by a chiral selector postmodification, named as HROP@SGS. Racemic 1-phenylethanol, ibuprofen, and naproxen could be separated only using such a piece of HROP@SGS as the filler with a solid phase extraction technique. Herein, HROP@SGS exhibited extraordinary chiral resolution performances and succeeded in achieving a complete chiral resolution. Our findings suggest that this simple strategy proposed by us, that is, combining the chiral micro/mesoporous organic materials with macroporous inorganic substrates, can be employed to prepare an unprecedented enantioseparation material, which has a promising potential in large-scale industrial applications, such as fixed-bed and membrane separation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.