Abstract
Purpose: Although conventional radiography is widely used for osteoarthritis (OA) diagnosis, it is not sensitive enough to detect early degenerative changes of cartilage. Indeed, disease process has frequently started for months or even years before a diagnosis is made. Therefore, functional imaging of OA is awaited in clinical practice, to probe tissue function and better evaluate disease progression. As such, positron emission tomography (PET) imaging method might fulfil these expectations, being further quantitative.
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