Abstract
This is the fourth yearly article in the Tourette Syndrome Research Highlights series, summarizing research from 2017 relevant to Tourette syndrome and other tic disorders. The authors briefly summarize reports they consider most important or interesting. The highlights from 2018 article is being drafted on the Authorea online authoring platform, and readers are encouraged to add references or give feedback on our selections using the comments feature on that page. After the calendar year ends, the article is submitted as the annual update for the Tics collection on F1000Research.
Highlights
This article is meant to disseminate recent scientific progress on Gilles de la Tourette Syndrome (TS)
A number of tic experts contributed to a review article on TS (Robertson et al, 2017)
Sample size (n=122) or the healthy control group may explain different results obtained by Abramovitch et al (2017), who studied treatment response in TS. They concluded that “the finding that significant change in symptom severity of TS/chronic tic disorder (CTD) patients is not associated with impairment or change in inhibitory control regardless of treatment type suggests that inhibitory control [as measured by the tests selected] may not be a clinically relevant facet of these disorders in adults.”
Summary
This article is meant to disseminate recent scientific progress on Gilles de la Tourette Syndrome (TS). They concluded that “the finding that significant change in symptom severity of TS/CTD patients is not associated with impairment or change in inhibitory control regardless of treatment type suggests that inhibitory control [as measured by the tests selected] may not be a clinically relevant facet of these disorders in adults.” Given these contradictory results, Morand-Beaulieu et al (2017b) review the puzzling question of inhibitory control in TS in a recent meta-analysis, and find larger inhibitory deficits in TS + ADHD patients, but this deficit was present in “pure” TS. Children showed no significant reduction in premonitory urges with treatment, even though CBIT was quite effective in the child study, and declines in urges in adults had no association with clinical improvement or group assignment.
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