Tourette's syndrome: Neurodevelopmental perspectives and implications for management

Abstract

Tourette Syndrome is a neurodevelopmental disorder affecting 1% of children and it is often mis-understood and under-diagnosed. The genetic heterogeneity in Tourette Syndrome links to clinical heterogeneity with presentations including varied symptomatology, associated features and co-morbidities such as Obsessive Compulsive Disorder and Behaviours, Attention Deficit Hyperactivity Disorder, and less commonly Autism Spectrum Disorder. This talk will aim to focus on the diagnostic process, differential diagnosis and co-morbidities as well as the role of genetic, neurobiological, and environmental factors in the pathogenesis including the translation of biological vulnerability to clinically significant symptoms.