Abstract

Introductions: Gastrectomy, which is the standard surgical procedure for gastric cancer, has gradually come to be performed laparoscopically. Laparoscopic distal gastrectomy (LDG) has been adopted gradually and performed for advanced gastric cancer. However, laparoscopic total gastrectomy (LTG) has not been as widely accepted as LDG due to technical difficulties, especially with reconstruction and proper D2 lymphadenectomy. The purpose of the current study was to determine the utility of TLTG with concomitant splenectomy and D2 lymphadenectomy (TLTGS) for advanced gastric cancer (AGC). Materials and Methods: Between January 2006 and May 2014, 10 consecutive patients who underwent TLTGS for AGC and 76 patients who underwent TLTG with D1 lymphadenectomy were included in this study. These two groups were compared in terms of perioperative results, with assessment of intraoperative and postoperative outcomes. Results: There were no significant differences in patients’ characteristics between the two groups. Operative time was longer in the TLTGS group than in the TLTG group. However, the rate of patients with postoperative complications including major complications was not different between the groups, and no patient in the TLTGS group had anastomotic leakage or pancreatic fistula. Conclusions: In the short-term, TLTGS had good postoperative outcomes and was useful and acceptable for AGC.

Highlights

  • Gastric cancer is one of the most common malignancies worldwide [1], and surgery offers the greatest chance of cure

  • The median number of dissected lymph nodes was 53 in the totally laparoscopic total gastrectomy (TLTG) with concomitant splenectomy and D2 lymphadenectomy (TLTGS) group and 29 in the TLTG group; it was significantly larger in the TLTGS group than in the TLTG group (P = 0.019)

  • For the histological type of cancer, there was a tendency for a lower degree of differentiation in the TLTGS group

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Summary

Introduction

Gastric cancer is one of the most common malignancies worldwide [1], and surgery offers the greatest chance of cure. Gastrectomy, which is the standard surgical procedure for gastric cancer, has gradually come to be performed laparoscopically. In 1994, the first report of laparoscopy-assisted distal gastrectomy (LDG) for early gastric cancer was published [2]. Laparoscopic total gastrectomy (LTG) for gastric cancer was first reported in 1999 [5], LTG has not been as widely accepted as LDG. The reasons for this are technical difficulties, especially with reconstruction and proper D2 lymphadenectomy. In TLTG, more advanced gastric cancer was associated with higher postoperative morbidity [8]. Evaluation of the safety and feasibility of D2 lymphadenectomy during TLTG would lead to wide acceptance of TLTG for advanced gastric cancer

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