Abstract
AbstractThe enantiospecific total synthesis of the cytotoxic guaipyridine sesquiterpene alkaloid (+)‐cananodine (1) is described. A chiral pool/chiral auxiliary based approach is described for the synthesis of a key oxazolidinone intermediate. Subsequent key steps involve diastereoselective oxazolidinone allylation, cycloheptenylmethanol formation using ring‐closing olefin metathesis, microwave‐assisted decarboxylative Claisen rearrangement reaction, and use of a novel pyridine‐forming method.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
