Abstract
The anthelmintic cyclooctadepsipeptide PF1022A and its antipode were synthesized starting from l-Nα-Boc-leucine (for PF1022A), d-Nα-Boc-leucine (for the antipode), l-lactic acid, and l-phenyllactic acid using Mitsunobu reaction and/or the DCC/HOBt method. The antipode had no anthelmintic efficacy.
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