Abstract
The first total synthesis of 15(RS)-5,6-dehydro-8- epi-PGF 2α methyl ester 1 with high stereoselectivity and good yield, is described using D-glucose as starting material. This novel isoprostane is a potent precursor of labelled (deutered and/or tritiated) 8- epi-PGF 2α, an useful tool for biological studies.
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