Total syntheses of (±)-α-acorenol, β-acorenol, α- epi-acorenol and β- epi-acorenol via an Ireland ester Claisen rearrangement and RCM reaction sequence

Abstract

Total syntheses of (±)-α- and β-acorenols and (±)-α- and β- epi-acorenols, spiro[4.5]decane sesquiterpenes, isolated from the western Australian sandalwood oil, have been accomplished employing a combination of Ireland ester Claisen rearrangement and RCM reactions for an efficient construction of the spiro[4.5]decane present in acoranes.