Total Peritoneal Gutter Removal versus Random Peritoneal Biopsy in Cases of Ovarian Cancer

Ahmed Abdel-Azeem Essmat,Mahmoud El-Sayed Meleis,Inass Ibrahim Ahmed Zaki,Helmy Abdel-Sattar Rady,Ahmed Shaaban Ali Ragab Khattab

doi:10.4236/ojog.2021.1110125

Abstract

Total Peritoneal Gutter Removal versus Random Peritoneal Biopsy in Cases of Ovarian Cancer

Highlights

Ovarian cancer is the fourth most prevalent cancer among women and the seventh most common cancer overall
Random peritoneal biopsy showed positive metastasis in 6 (4.6%) cases and free in 124 (95.4%) cases while total peritoneal gutter removal showed positive metastasis in 19 (14.6%) cases and free in 111 (85.4%) with Chi-square test was 7.479 and P value was 0.004 which is statistically significant. 108 (97.3%) cases had negative random peritoneal biopsy and negative total peritoneal gutter removal, 3 (2.7%) cases had positive random peritoneal biopsy and negative total peritoneal gutter removal, 16 (84.2%) cases had positive total peritoneal gutter removal and negative random peritoneal biopsy & 3 (15.8%) cases had positive total peritoneal gutter removal and positive random peritoneal biopsy with Chi-square test 6.311, FEp 0.04 and Kappa test 0.183 (0.012) which is statistically significant with poor strength of agreement
In comparison of total peritoneal gutter removal to random peritoneal biopsy, the results showed sensitivity 15.79%, specificity 97.3%, positive predictive value 50%, negative predictive value 87.1% with accuracy 85.38%

Summary

Introduction

Ovarian cancer is the fourth most prevalent cancer among women and the seventh most common cancer overall. The aim of this work was primarily to compare the differences between total peritoneal gutter removal and random peritoneal biopsy in cases of early ovarian cancer. A secondary aim of this work is to show ability of total peritoneal gutter removal in relation to that of random peritoneal biopsy to detect positivity of metastasis in the histopathological specimens. An estimated 200,000 cases and 125,000 deaths related to ovarian cancer are reported around the world It is most common in high-resource countries, with an incidence rate of 9.3 per 100,000 women [1].

Objectives

Methods

Results

Conclusion