Abstract

Complete obstruction of the left main coronary artery (LMCA) is an intriguing, rare angiographic and pathologic finding. Etiologic factors accountable for total LMCA occlusion include a variety of pathologic processes as well as iatrogenic mechanisms. Despite the crucial anatomic location of the occlusion and its severe interference with the left ventricular function, clinical presentation may vary considerably. The purpose of this review is fourfold: to delineate the etiology of total left main occlusion; to describe clinical manifestations; to report related angiographic findings; and to discuss therapeutic options for treatment of patients presenting with this unique condition.

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