Abstract
Background and Aims: It is well-established that microcalcifications in the cap area and haemorrages through leaky neovessels destabilise atherosclerotic plaque whereas macrocalcifications prevent its rupture. Yet, distinct patterns of angiogenesis and calcification might differentially affect plaque progression. Here we examined the contribution of angiogenesis to neointimal calcification and assessed an impact of neovascularisation-related calcification on plaque progression.
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