Abstract
TOR: the first ten years.- The role of phosphatases in TOR signaling in yeast.- Yeast TOR signaling: a mechanism for metabolic regulation.- Nutrient signaling through TOR kinases control gene expression and cellular differentiation in fungi.- Autophagy in yeast: a TOR-mediated response to nutrient starvation.- The fission yeast TOR proteins and the rapamycin response: an unexpected tale.- Plant growth and the TOR pathway.- TOR action in mammalian cells and C. elegans.- Genetic analysis of TOR signaling in Drosophila.- Interplay between growth factor and nutrient signaling: lessons from Drosophila TOR.- mTOR signaling to translation.- Modulation of the protein kinase activity of mTOR.- Role of mTOR signaling in the control of translation initiation and elongation by nutrients.- Novel regulatory mechanisms of mTOR signaling.- Raptor and mTOR: subunits of a nutrient-sensitive complex.- Kinase activities associated with mTOR.- mTOR: a mediator of intracellular homeostasis.- mTOR as a positive regulator of tumor cell response to hypoxia.- Retroviral oncogenes and TOR.- mTOR as a target for cancer therapy.- Subject index.
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