Topographic organization of peripheral trigeminal ganglionic projections in newborn rats

Abstract

Retrograde transport of fluorescent tracers (true blue and diamidino yellow) was employed to delineate the topography of the peripheral projections of trigeminal ganglion cells in newborn (<12 h of age) rats. Identical injections were made in adult animals for comparison. In neonates, both inter- and intradivisional topography of ganglionic projections were adult-like. Neurons which innervated mandibular fields were located posterolaterally while cells with ophthalmic or maxillary projections were restricted to the anteromedial and central parts of the ganglion, respectively. An adult-like topographic representation of the mystacial vibrissae follicles was also evident in the neonates.