Abstract
A method has been worked out to determine the site of plasma protein loss in proteinlosing gastroenteropathies. It uses the ratio between faecal excretion of 125I and 131I following simultaneous i.v. injection of 125I-IgG and 131I-albumin. 165 cases were studied (Menetrier's disease, 12 cases; intestinal lymphangiectasia, 19; adult coeliac disease, 6; other small-intestinal diseases, 5; chronic inflammatory bowel disease, 115 (83 of whom had Crohn's disease and 32 ulcerative colitis); and neoplastic diseases, 8 cases). Gastrointestinal macromolecular leakage was detected and semiquantitated by means of 51CrCl3 (33 cases) or 59Fe-iron dextran (90 cases). Faecal 59Fe clearance was significantly (p 200g/day) in the other groups. Faecal radioiodide ratio (125I/131I) was inapplicable in 2...
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
