Abstract
Topiramate for Abnormal Eating Behaviour in Frontotemporal Dementia: Topiramate is a sulfamate-substituted monosaccharide anticonvulsant that is associated with anorexia and weight loss and has been used to treat binge eating disorder and bulimia nervosa. This report describes a man with frontotemporal dementia, behavioural variant, associated with abnormal eating behaviour which appeared to respond to topiramate. We review the physiological basis of abnormal eating behaviour in frontotemporal dementia and explore possible mechanisms of action by which topiramate may modify eating behaviour in this condition.
Highlights
Topiramate is a sulfamate-substituted monosaccharide anticonvulsant that has been associated with anorexia and weight loss [1] and been found to be of benefit in binge eating disorder [1] and bulimia nervosa [2]
We describe a case of a patient with frontotemporal dementia associated with abnormal eating behaviour which responded to topiramate
We demonstrated that topiramate improved abnormal eating behaviour in bvFTD when other pharmacotherapy directed at challenging behaviours had failed
Summary
Topiramate is a sulfamate-substituted monosaccharide anticonvulsant that has been associated with anorexia and weight loss [1] and been found to be of benefit in binge eating disorder [1] and bulimia nervosa [2]. We describe a case of a patient with frontotemporal dementia associated with abnormal eating behaviour which responded to topiramate
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
