Topical timolol ophthalmic solution causing remarkable improvement in an ulcerated facial hemangioma

Abstract

Infantile hemangiomas usually regress spontaneously and do not need treatment as active nonintervention is considered the gold standard. However, facial lesions cause significant distress to parents and are associated with a risk of scarring, disfigurement, and airway obstruction, apart from syndromic associations. The management of infantile hemangiomas has changed considerably in the last few years with the advent of topical timolol preparations. We describe the first case of an infant with an ulcerated, superficial, perioral, and segment three hemangioma, who responded dramatically to topical timolol 0.5% ophthalmic solution within 2 months. We suggest that timolol ophthalmic solution may be an option for such lesions under close monitoring.