Abstract
Topical glucocorticoids are among the most widely used medications in dermatology. Chronic use of applied steroids leads to atrophic changes, but the mechanism underlying this thinning process is unclear. Nuutinen and colleagues recently tested the hypothesis that modulation of mRNA levels in the dermal fibroblasts may contribute to steroid-induced atrophy. The investigators designated 3 areas on the abdomen of each of 9 healthy volunteers as …
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