Topical Sodium Diclofenac during Pan-Retinal Photocoagulation in Patients with Proliferative Diabetic Retinopathy

Abstract

Aim:To determine the 0.1 percent topical sodium diclofenac analgesic effect on the retina during laser photocoagulation. Study Design: Arandomized prospective control study. Place and Duration:In the Ophthalmology department of Hayatabad Medical complex Peshawar and Woman Medical and Dental College, Abbottabad for duration of six months from November 2020 to April 2021. Methods:The study included 90 people with 47 cases of proliferative diabetic retinopathy who had two sessions of pan-retinal photocoagulation (group A) as well as 43 people with non-proliferative diabetic retinopathy who received bilateral grid treatment (group B) (group B).sodium chloride 0.9% or Sodium diclofenac 0.1% topical drops were instilled 30–135 mints formerly to treatment with laser in a concealed fashion.When a patient had 2 sessions, the alternative medicine was administered in the second session. The visual analogue scale was castoff to measure the amount of pain immediately after the laser therapy (VAS). The findings were subjected to statistical analysis Results: In 84/90 sessions, patients in A grouptestifiedpain (93.3 percent). When 0.1 percent sodium diclofenac drops were instilled, the mean stated grade of pain was 47.8 percent, and when 0.9 percent sodium chloride drops were instilled, the mean reported degree of pain was 53.3 percent. Only 14/60 sessions (23.3 percent) of patients in group B reported pain, and pain levels varied from 10% to 60% depending on the kind of drops administered. There was no link between pain intensity and the time it took to go from applying the drops to laser therapy (30–135 minutes) or the average energy level utilized (100–500 mW) in either group. Conclusion:Pan-retinal photocoagulation should be performed after the administration of sodium diclofenac 0.1 percent, which is an excellent pain reliever.