Abstract
Noble metal particles, especially gold (Au) and silver (Ag) nanoparticles exhibit unique and tunable optical properties on account of their surface plasmon resonance (SPR). It can be widely used in the field of immunoassay. In this paper, we reviewed the design, fabrication methods and applications of the nanoparticles. Discrete dipole approximation (DDA) and finite difference time domain (FDTD) methods applied brute-force computational methods for calculation and analysis of optical properties of different nanoparticles. Current nanotechnologies such as focused ion beam (FIB), nanosphere lithography (NSL), and laser interference lithography (LIL) make it possible to fabricate nanoparticles with arbitrary shapes. These nanoparticles are used to detect binding signals excited from biosamples for immunoassay such as antibody and antigen, amyloid-derived diffusible ligands (ADDLs)-potential Alzheimer's disease (AD) biomarkers, and Staphylococcal enterotixn B (SEB) in the concentration of nano-Moore per liter (nM) level. Finally, a biochip with multi-channel detection of biotin-streptavidin based on localized surface plasmon resonance was introduced. Copyright © 2010 American Scientific Publishers
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Computational and Theoretical Nanoscience
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
