Abstract
Certain sulfonamides derived from butanesulfonic acid are repellent to female Aedes uegypti mosquitoes. Exploration of the structure-activity relations revealed that the boiling point is the most important factor controlling duration of activity as topical repellents. Quinoline-4-carboxylic acid derivatives were explored for their repellency, and amides were found less active than were esters, primarily due to their low volatility. Certain sulfonamides derived from butanesulfonic acid are repellent to female Aedes uegypti mosquitoes. Exploration of the structure-activity relations revealed that the boiling point is the most important factor controlling duration of activity as topical repellents. Quinoline-4-carboxylic acid derivatives were explored for their repellency, and amides were found less active than were esters, primarily due to their low volatility.
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