Topical Management of Chronic Rhinosinusitis

Abstract

Abstract Chronic rhinosinusitis (CRS) is an inflammatory condition involving nasal passages and therefore the paranasal sinuses for 12 weeks or longer [1]. It are often subdivided into three types: CRS with nasal polyposis (CRS with NP), CRS without nasal polyposis (CRS without NP), and Allergic fungal rhinosinusitis (AFRS). To diagnose CRS we require a minimum of two of 4 of its cardinal signs/symptoms. Additionally, direct visualization or imaging for objective documentation of mucosal inflammation is required. CRS therapy is aimed to scale back its symptoms and improve quality of life because it can't be cured in most patients. Thus, the goals of its therapy include the following: • Control mucosal edema and inflammation of nasal and paranasal sinuses • Maintain adequate sinus ventilation and drainage • Treat any infecting or colonizing micro-organisms, if present • Reduce the amount of acute exacerbations Mucosal remodeling is that the presumably underlying mechanism causing irreversible chronic sinus disease, almost like that happens in severe asthma [2]. In patients with both disorders, medical treatment of CRS can help in asthma control. Multiple topical and systemic therapies are utilized in the management of CRS, including saline washes and sprays, intranasal and systemic glucocorticoids, anti-leukotriene agents, and antibiotics.