Abstract
This study aimed to do a review of the literature regarding the use of topic iodine and/or compounds in the treatment of chronic wounds. The clinical trials were searched in the Cochrane database. Fourteen (58.3%) among 24 studies fulfilled the inclusion criteria. The articles were analyzed regarding journal and study characteristics and classified into three groups: Iodine versus other topic agents (7/ 50%); Iodine versus different dressings (6/ 42.9%); Iodine versus without Iodine (1/ 7.1%). Favorable results for the use of Iodine or similar product occurred in 50% of the analyzed studies. Six out of 8 trials showed favorable results for healing and infection prevention/ treatment; 4 out of 5 were not favorable when the healing objective was investigated and 1 study for infection treatment showed no favorable result.
Highlights
IntroductionMETHODThe development of antiseptics is related to the history of wound treatment. Their basic objectives are to reduce risks and prevent or reduce infectious complications.Antiseptics are hypoallergic substances, of low causticity, which possess lethal or inhibiting action of microbial reproduction, for application on skin and mucous tissues[1].For more than a century, iodine was considered one of the most efficacious antiseptics
METHODThe development of antiseptics is related to the history of wound treatment
The results show that the first publication on the use of iodophors in chronic wounds occurred in 1980 and that the largest number of publications appeared in the 1980s (9/64.3%)
Summary
METHODThe development of antiseptics is related to the history of wound treatment. Their basic objectives are to reduce risks and prevent or reduce infectious complications.Antiseptics are hypoallergic substances, of low causticity, which possess lethal or inhibiting action of microbial reproduction, for application on skin and mucous tissues[1].For more than a century, iodine was considered one of the most efficacious antiseptics. The development of antiseptics is related to the history of wound treatment. Their basic objectives are to reduce risks and prevent or reduce infectious complications. For more than a century, iodine was considered one of the most efficacious antiseptics. Discovered in 1812 by the French scientist Dijon Bernad Courtors, it was only denominated iodine in 1814 by Gay Loussac. The word originates from the Greek word ioidés and refers to the purple color of its vapor[2]. It was officially recognized by the United States Pharmacopea in 1830. In 1839, the first report was made of its specific use in wounds
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