Topical Clascoterone: A Potential Treatment for a Hidradenitis Suppurativa Subgroup

Abstract

This commentary is a follow-up to the article “Use of topical clascoterone for the treatment of hidradenitis suppurativa [1]”. In this article, we described the successful treatment of a 23-year-old female with Hurley stage 1 Hidradenitis Suppurativa (HS) with topical clascoterone 1% cream [1]. With a waxing and waning course, HS is a chronic and debilitating inflammatory skin disease that often requires multiple treatments [2]. Inadequately treated painful nodules and abscesses in intertriginous areas can subsequently develop into fistulae, draining sinus tracts, and scars [2,3]. Thus, while many clinical trials are focused on the population of patients with moderate to severe disease, treatment of HS early in the disease course is of paramount importance, to improve both the characteristic HS lesions and the quality of life of affected patients [2].