Abstract
Oral mucositis is one of the most uncomfortable and common complications of chemotherapy. Inflammation which is initiated by release of free radicals from oral mucosal tissue exposed to anticancer drug is involved in the development of oral mucositis. Therefore, it is expected that antioxidant and anti-inflammatory effect of sesame oil may be effective for the prevention of chemotherapy-induced oral mucositis. In the present study, effects of topical application of sesame oil on the chemotherapy-induced oral mucositis were evaluated.
Highlights
MethodsEleven patients who had been admitted to the general hospital for the chemotherapy of hematopoietic cancer received an explanation of the study and those whose consents were obtained participated in the study
Jing-Well points, Acupuncture, Moxibustion, Bloodletting puncture, Laser acupuncture, Electroacupuncture, Acupressure subjects’ impressions about sesame oil application were evaluated
Cytological examination revealed that inflammatory change was reduced in sesame oil application group compared to control group. 5 of 7 subjects who had experienced mucositis in previous chemotherapy session felt that sesame oil was effective for the prevention of oral mucositis
Summary
Eleven patients who had been admitted to the general hospital for the chemotherapy of hematopoietic cancer received an explanation of the study and those whose consents were obtained participated in the study. Sesame oil of Japanese Pharmacopoeia grade (Nikko Pharmaceutical, Japan) was used for application.
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