Abstract

Each year the physician-editors of Journal Watch Cardiology select the stories published during that year that they believe had the greatest impact on cardiovascular diagnosis and treatment. Here are highlights from our choices for 2006. Several important studies addressed strategies involving clopidogrel. In the CHARISMA trial, the addition of clopidogrel to aspirin did not improve outcomes in high-risk, stable patients. In the ACTIVE W trial, clopidogrel plus aspirin was inferior to oral anticoagulation therapy in preventing stroke, systemic embolism, MI, or vascular death …

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