Abstract
AbstractThe relation of alveolar clefts to morphogenesis of teeth in the line of the cleft was explored. The oral‐facial‐digital (OFD) syndrome is a unique experiment of nature wherein the position of the cleft is posterior to where it occurs in the more common types of cleft. In the latter the cleft occurs anterior to the maxillary canine and affects the number and form of the lateral incisor. In the OFD syndrome the cleft occurs posterior to the canine with duplicate canines, sometimes “T”‐shaped, occurring on either side of the alveolar cleft. These findings suggest a common timespace relation between alveolar clefting and tooth‐bud formation, probably occurring in the sixth week of embryonic life.
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