Abstract
Tonsillectomy increases the liability to the subsequent development of Hodgkin's disease by a factor of 2.9 times. Since appendicectomy has previously been shown to increase the liability to subsequent Hodgkin's disease, it seems that surgical ablation of active lymphoid tissue, and perhaps the natural involution in late childhood of the oropharyngeal lymphoid tissue, in some way facilitate the onset of Hodgkin's disease. A protective barrier is removed.
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