Abstract
Abstract Background Changes in arterial compliance are among the first changes detectable in hypertensive syndrome. Methods with good reproducibility as compared with the gold standard for identifying such changes are desirable in clinical practice. Objectives To compare central pressure measurements and arterial stiffness obtained by two non-invasive methods (tonometry and oscillometry). Methods This was a descriptive, cross-sectional study with a convenience sample of patients with borderline hypertension or stage 1 hypertension. Peripheral and central blood pressure measurements were obtained by tonometry (SphygmoCor®), considered the gold standard, and oscillometry (Mobil O´graph®). Comparisons of results were made by unpaired t-test, and p values 0.05). Mean pressure wave velocity (PWV), 8.4 m/s vs. 7.4 m/s (p = 0.013) and mean central pulse pressure, 37.7 mmmHg and 30.9 mmHg (p = 0.013) were significantly higher by SphygmoCor® than Mobil O´graph®. Conclusion Values of central systolic blood pressure, AIx and pulse pressure amplification obtained by oscillometry were not statistically different compared with tonometry; values of PWV and cPP, however, were underestimated by oscillometry. (Int J Cardiovasc Sci. 2020; 33(2):145-150)
Highlights
Guidelines for the management of hypertension have recommended an early diagnosis and treatment of arterial hypertension as a fundamental strategy to reduce the occurrence of cardiovascular events.[1,2,3] In this regard, the use of biomarkers can increase the accuracy of the diagnosis, especially in patients with borderline hypertension and in patients with stage 1 hypertension
Values of central systolic blood pressure, augmentation index (AIx) and pulse pressure amplification obtained by oscillometry were not statistically different compared with tonometry; values of pulse-wave velocity (PWV) and central pulse pressure (cPP), were underestimated by oscillometry. (Int J Cardiovasc Sci. 2020; 33(2):145-150) Keywords: Hypertension; Risk Factors; Blood Pressure; Vascular Stiffness
The study was approved by the ethics committee of the General Hospital of the Federal University of Goias This is one of the sub-studies of the original project entitled “Correlação entre Valores Obtidos na Medida Central da Pressão Arterial com a Espessura das Camadas Íntima e Média das Artérias Carótidas em Pacientes com Pressão Arterial Sistêmica Limítrofe ou Hipertensos Estágio 1”
Summary
Guidelines for the management of hypertension have recommended an early diagnosis and treatment of arterial hypertension as a fundamental strategy to reduce the occurrence of cardiovascular events.[1,2,3] In this regard, the use of biomarkers can increase the accuracy of the diagnosis, especially in patients with borderline hypertension and in patients with stage 1 hypertension. In these patients, in up to 18% of the cases, cardiovascular risk is underestimated by the conventional risk stratification model.[4,5]. Methods with good reproducibility as compared with the gold standard for identifying such changes are desirable in clinical practice
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