Abstract
The presence of megaloblasts and macrocytes in the bone marrow characterizes megaloblastic anaemia. Megaloblastic anaemia is the result of folate and vitamin B12 deficiency in more than 95% of cases. We hereby report a case of megaloblastic anaemia in a 23-year old female having glossitis and a burning sensation on the tongue. The blood picture showed megaloblastic anaemia and haematological tests confirmed the diagnosis. The patient positively responded to vitamin B12 and folic acid supplementation. The presence of oral signs and symptoms offer the dentist an opportunity to participate in the diagnosis of this condition. Early diagnosis is important to prevent deficiency. This paper explains the oral changes induced by dietary deficiency of cobalamin or folate in a patient with megaloblastic anaemia.
 Update Dent. Coll. j: 2021; 11 (1): 26-28
Highlights
Megaloblastic anemia (MBA), known as macrocytic anemia, is characterized by a decreased number of RBCs as well as the presence of unusually large, abnormal, and poorly developed erythrocytes(megaloblasts), and because of the greater size, they are unable to enter the bloodstream[1]
The tongue was mild blackish pigmented for 3-4 months due to use of charcoal toothpaste
After taking her history and clinical examination we advised her to stop the use of charcoal toothpaste and suggested using baby toothpaste
Summary
Update Dental College Journal (UpDCJ): Vol- 11, Issue-1 evident. The tongue was little puffy dorsally. The tongue was mild blackish pigmented for 3-4 months due to use of charcoal toothpaste. After taking her history and clinical examination we advised her to stop the use of charcoal toothpaste and suggested using baby toothpaste. Based on the patient's history and clinical examination, she was prescribed vitamin A, C, E supplements once daily for 15 days, as well as povidone-iodine mouthwash. She was later advised to undergo haematological tests. The patient was advised to modify her diet by taking nutritious food She was suggested to take diets rich in folic acid like spinach, lettuce, eggs, liver. Figure: Follow up after 1 month: significantly reduced features of glossitis but not completely resolved
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