Abstract
The outbreak of novel coronavirus disease (2019-nCoV or COVID-19) is responsible for severe health emergency throughout the world. The attack of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is found to be responsible for COVID-19. The World Health Organization has declared the ongoing global public health emergency as a pandemic. The whole world fights against this invincible enemy in various capacities to restore economy, lifestyle, and safe life. Enormous amount of scientific research work(s), administrative strategies, and economic measurements are in place to create a successful step against COVID-19. Furthermore, differences in opinion, facts, and implementation methods laid additional layers of complexities in this battle against survival. Thus, a timely overview of the recent, important, and overall inclusive developments against this pandemic is a pressing need for better understanding and dealing with COVID-19. In this review, we have systematically summarized the epidemiological studies, clinical features, biological properties, diagnostic methods, treatment modalities, and preventive measurements related to COVID-19.
Highlights
The emergence and spread of 2019 novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) has threatened global public health
A successful immunological field-effect transistor (FET)-based biosensing device was developed for detecting SARS-CoV-2 in clinical samples, where the sensor was developed by conjugating a specific antibody against SARS-CoV-2 spike protein to graphene sheet coated FET [64]
Liu et al [111] reported that 188 patents are directly associated with anti-SARS and anti-Middle East Respiratory Syndrome (MERS) vaccines (15 patents on inactive and live-attenuated virus vaccines, 28 patents on DNA vaccines, 21 patents on viral vector vaccines, 13 patents on virus-like particle (VLP) vaccines, and three patents on mRNA vaccines) with a demonstrated immune response, which could be a huge boost for COVID-19 vaccine developers
Summary
The emergence and spread of 2019 novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) has threatened global public health. Research, where a maximum and a very large obtained in 2020 on both the keywords in comparison to previous years (Figure 1B). 2020 on both the keywords in comparison to previous years reported global publishing phenomenon on COVID-19 pandemic We provide an overview of conflicts and controversies is the need of the time to set a clear directive in this battle Through this updated and rapidly evolving progress against COVID-19 pandemic including various conflicts to review article, we provide an overview of updated and rapidly evolving progress against COVID-19 the readers in a comprehensive manner. Areas covering current known properties of SARS-CoV-2, diagnostic tools properties for detection, we have the summarized diversebiological research areas covering the current known biological of therapeutic measurements for possible treatment, and prevention techniques to stop further spreading. Disease” keyword for last 10 years (2020–2011) according to PubMed (data accessed on 24th July, 2020)
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