Abstract
Pulsed lasers in photoacoustic tomography systems are expensive, which limit their use to a few clinics and small animal labs. We present a method to realize tomographic ultrasound and photoacoustic imaging using a commercial LED-based photoacoustic and ultrasound system. We present two illumination configurations using LED array units and an optimal number of angular views for tomographic reconstruction. The proposed method can be a cost-effective solution for applications demanding tomographic imaging and can be easily integrated into conventional linear array-based ultrasound systems. We present a potential application for finger joint imaging in vivo, which can be used for point-of-care rheumatoid arthritis diagnosis and monitoring.
Highlights
In photoacoustic (PA) imaging, pulsed or modulated light induces thermoelastic expansion in optical absorbers resulting in ultrasound (US) signals, which are detected to form an image [1]
It can be observed that structural similarity (SSIM) and peak signal-to-noise ratio (PSNR) do not significantly improve beyond 16 angular views
Through our results we have successfully demonstrated photoacoustic and ultrasound tomographic imaging using an LED-based illumination and linear transducer array-based acoustic detection
Summary
In photoacoustic (PA) imaging, pulsed or modulated light induces thermoelastic expansion in optical absorbers resulting in ultrasound (US) signals, which are detected to form an image [1]. This emerging modality can surpass the high optical scattering in biological tissue by exciting the tissue with light and detecting relatively less scattered US [2]. Linear transducer arrays offer real-time imaging and are widely used in clinics they are preferred for combined PA and US imaging [9,10,11]. An inexpensive, compact and real-time tomographic imaging system that performs combined PA and US imaging can be advantageous to leverage the potential of this new modality for wide clinical use
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
