Abstract
Prior research has indicated low tumor Toll-like receptor 9 (TLR9) expression is associated with worsened disease-specific survival in patients with triple-negative breast cancer (TNBC), but not hormone receptor positive (ER+, PgR+, Her-2-) breast cancer in a Finnish Caucasian population. An inverse relationship between survival and TLR-9 status has been detected in renal cell carcinoma in a similar, highly homogenous population. The aim of this study was to evaluate TLR9 expression in a population of African American TNBC patients and assess its relationship to survival and recurrence.
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