Abstract
Single-agent treatment of hypertension with either a j1-blocker or a calcium antagonist sometimes fails to adequately control blood pressure (Daniels & Opie 1986). Therefore, it may be reasonable to attempt combination therapy, for example, using atenolol plus nifedipine. This paper describes an on-going study of this j1-blocker and calcium antagonist combination designed to evaluate blood pressure control, incidence of unwanted effects, and biochemistry and haematology. The appropriate dose frequency and dosage of the 2 constituents of the combination was also evaluated.
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