Abstract
We read with interest the study of Giovanni Guaraldi and colleagues1 on the use of tocilizumab in patients with COVID-19. We congratulate the authors for their effort to assess the effects of tocilizumab in patients with COVID-19, and for the promising results achieved. We wish to suggest a word of caution about the absence of association between the use of tocilizumab and liver injury in their study. Liver function test abnormalities occurred in up to 50% of patients treated with tocilizumab in registration trials, and cases of severe liver injury have been described after tocilizumab licensure.
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