Abstract

Tobacco use started several centuries ago and increased markedly after the invention of the cigarette making machine. Once people start smoking they find it difficult to quit the habit. This is due to the addictive effect of nicotine in tobacco smoke. Various epidemiologic and laboratory studies clearly showed that smoking is associated with various diseases such as heart diseases, asthma and emphysema and the associated increase in morbidity and mortality of smokers. Several studies implicate nicotine as the causative factor in tobacco smoke. Apart from nicotine, various carcinogens also occur in tobacco smoke resulting in an increase in the incidence of cancer in smokers. While the smoking habit is decreasing in developed countries, tobacco use increases in the developing countries. Smoking prevalence is also highest in poor communities and amongst those with low education levels. It is important to note that, although ther is a decline in the number of smokers in the developed countries, there is a three to four decades lag between the peak in smoking prevalence and the subsequent peak in smoking related mortality. It has been shown that maternal smoking induces respiratory diseases in the offspring. There is also evidence that parental smoking may program the offspring to develop certain diseases later in life. Various studies showed that maternal nicotine exposure during pregnancy and lactation via tobacco smoke of nicotine replacement therapy (NRT), program the offspring to develop compromised lung structure later in life with the consequent compromised lung function. This implies that NRT is not an option to assist pregnant or lactating smokers to quit the habit. Even paternal smoking may have an adverse effect on the health of the offspring since it has been shown that 2nd and 3rd hand smoking have adverse health consequences for those exposed to it.

Highlights

  • Tobacco is used since around the first century BC by Native Americans for ceremonial purposes

  • Various studies showed that maternal nicotine exposure during pregnancy and lactation via tobacco smoke of nicotine replacement therapy (NRT), program the offspring to develop compromised lung structure later in life with the consequent compromised lung function

  • Recent studies suggest that many of the diseases associated with tobacco smoke are induced by nicotine, the addictive substance in tobacco (Maritz & Windvogel, 2003; Petre et al, 2011; Sekhon, Keller, Benowitz, & Spindel, 2001). These diseases adversely impact on the productivity of individuals exposed to first, second, and third hand smoke in that it adversely impact on the health of such persons and increased hospital admissions

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Summary

Introduction

Tobacco is used since around the first century BC by Native Americans for ceremonial purposes. Recent studies suggest that many of the diseases associated with tobacco smoke are induced by nicotine, the addictive substance in tobacco (Maritz & Windvogel, 2003; Petre et al, 2011; Sekhon, Keller, Benowitz, & Spindel, 2001) These diseases adversely impact on the productivity of individuals exposed to first, second, and third hand smoke in that it adversely impact on the health of such persons and increased hospital admissions. According to reports the lifespan of tobacco users is reduced by about 13 to 14 years compared to that of non-smokers (CDC report, 2002) This figure does not take the effect of maternal smoking or maternal use of nicotine to quit smoking during pregnancy on the health and lifespan of the offspring in the longer term into consideration. The objective of this review is to: 1) record the factors determining patterns of smoke exposure by smokers and non-smokers, 2) report on the consequences of maternal exposure to tobacco smoke and/or nicotine on the health of the offspring, especially in the longer term, and 3) discuss the appropriateness of NRT to assist especially pregnant and lactating mothers to quit the habit

First Hand Smoke Exposure
Second Hand Smoke Exposure
Third Hand Tobacco Exposure
Developed Countries
Developing Countries
Disease Patterns Related to Tobacco Smoke
Current Mortality and Disability from Smoking
Behavior Patterns of the Offspring
Maternal Smoking and Disease in the Offspring
Maternal Nicotine Exposure and Health of the Offspring
Smoking and Nicotine and the Placenta
Nicotine and the Lung
Nicotine Replacement Therapy
Findings
Key Messages for the Individual Smoker
Full Text
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