Abstract
Objective: To determine the relationship between tobacco and alcohol consumption and staging of head and neck cancer in patients treated at a referral hospital for cancer treatment. Material and Methods: This is a cross-sectional study based on medical records of patients with head and neck cancer treated between 2008 and 2015. The following variables were considered: gender, age, marital status, educational level, place of residence, profession, affected site, clinical staging of neoplasms, histopathological diagnosis, tobacco and alcohol consumption . Results: Of the 154 medical records analyzed, there was predominance of male patients (72.7%), single (50%), with low education (88.1%), rural workers (38.3%), residents in the state countryside (70.2%) and aged 20-94 years. T3 and T4 size tumors prevailed. Significant correlation was found between alcohol use and tumor size (p=0.03) and presence of nodules (p<0.001), as well as between alcohol use and smoking with tumor size (p=0.04) and presence of nodules (p=0.019). No correlations were observed between tobacco use and injury staging. Conclusion: There was strong significance between tumor size and presence of nodules, both with the use of alcohol alone and with tobacco, thus suggesting the existence of important carcinogenic action of this substance.
Highlights
Head and neck cancer (HNC) is a complex malignant neoplasm that involves vital anatomical structures, which makes its treatment difficult [1]
The present study investigated the relationship between the use of alcoholic beverages and tumor size, presence of nodules and metastases related to the clinical staging of the lesion
Results found in this study indicate that the association between "heavy" alcohol and tobacco consumption and tumor size is consistent
Summary
Head and neck cancer (HNC) is a complex malignant neoplasm that involves vital anatomical structures, which makes its treatment difficult [1]. The National Cancer Institute's estimates for the 20182019 biennium stipulate that, for Brazil, 11,200 new cases of oral cavity cancer among men and 3,500 among women will appear each year, while for laryngeal cancer, estimates are 6,390 new cases among men and 1,280 among women each year [2]. Despite the fact that the survival pattern for individuals with oral cancer is 50%, very little has been done in an attempt to correlate the influence of risk factors on the appearance of potentially malignant lesions and oral cancer [3]. Alcohol and tobacco are recognized worldwide as the most important risk factors for the development of squamous cell carcinoma of the oral cavity and pharynx and have a synergistic effect [2,4]. In general, "heavy" smokers are "heavy" drinkers, and sometimes the assessments of the effects of these habits alone are inconsistent [5]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
