To the question of the treatment of typhoid fever with a vaccine on an Occasional basis

Abstract

To combat typhoid fever, we still do not have a well-developed specific therapy. The serum offered by Chantemess had to be abandoned due to the severity of the phenomena associated with its use. The improvement of the methods of its preparation and application (the combined Rod method), although it gives very comforting results according to French authors, is still under development. The question of vaccine therapy has been developed in much more detail here, mainly by Prof. Lavrinovich and Prof. Granstrom, from whose works it is clear that the best effect is obtained from the intravenous method of administration of the vaccine, which in many cases gave an abortive course of abdominal pain. typhus. Nevertheless, despite this, the vaccine therapy of br. typhus has not become widespread enough due to a number of contraindications to it (heart weakness, tuberculosis, pregnancy), as well as due to the constraint of its use (no later than the 10th day) and the appearance of some complications. Therefore, it is quite understandable to turn to a simpler and less harmless method, namely to vaccinotherapy per os on an Occasional basis.