To the question of prenatal predisposing factors to allergic diseases

Abstract

Background. To study the peculiarities of pregnancy in asthma women and the health status of their children. Materials and methods. We examined the natural course and outcomes of pregnancy of 1010 women with asthma and monitored health status of their children up to 7 years old. Women were under the observation of pulmonologist and obstetrician throughout the period of gestation; they were treated if necessary and provided with recommendations for the primary prevention of allergic diseases in unborn child. Immediately after delivery children were under the supervision of a pediatrician, allergist. Results. Rising incidence of pregnancy complications in patients with asthma is directly related to the lack of control of the disease, especially in the first trimester of gestation. The lack of adequate treatment of asthma increases the risk of threatened abortion (OR 1,76, CI 0,90-3,47), preeclampsia (OR 2,77, CI 0,94-8,14), placental insufficiency (OR 2,45, CI 1,04-5,87), which has a direct effect on the formation of allergic diseases and, particularly, asthma in their children. Conclusion. Even severe asthma, is not a contraindication for pregnancy. The basic condition for the safety pregnancy and delivery is the adequate medical care that is a set of preventive and therapeutic measures for control of the disease that improve the quality of life of women during gestation and reduce the risk of allergic disease in their children.